October 7, 2024 – CounterX Therapeutics

October 7, 2024 in Publications

ACS Omega: Structure-Based Engineering of Monoclonal Antibodies for Improved Binding to Counteract the Effects of Fentanyl and Carfentanil

Rodarte J, Baehr C, Hicks D, McGovern M, Zhang Y, Silva-Ortiz P, Hannon B, Duddu S, Pancera M, Pravetoni M. ACS Omega. 2024 Oct 7;9(41):42506-42519. doi: 10.1021/acsomega.4c06617. PMID: 39431098

Psychopharmacology: A humanized monoclonal antibody attenuates fentanyl self-administration and reverses and prevents fentanyl-induced ventilatory depression in rhesus monkeys

ACS Omega: Structure-Based Engineering of Monoclonal Antibodies for Improved Binding to Counteract the Effects of Fentanyl and Carfentanil

The Journal of Immunology: Monoclonal Antibodies Engineered with Fc Region Mutations to Extend Protection against Fentanyl Toxicity

Expert Opinion Investigational Drugs: The potential role of opioid vaccines and monoclonal antibodies in the opioid overdose crisis

Structure: Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding

Human Vaccines & Immunotherapeutics: Advancing humanized monoclonal antibody for counteracting fentanyl toxicity towards clinical development

ACS Omega: Structure-Based Engineering of Monoclonal Antibodies for Improved Binding to Counteract the Effects of Fentanyl and Carfentanil